作者: David R Fogelman , Scott Kopetz , Cathy Eng
DOI: 10.1517/14728210802544575
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摘要: Background: The past 5 years have shown major advances in the treatment of colorectal cancer. Our understanding existing drugs, such as oxaliplatin and irinotecan, has become more refined. incorporation newer drugs bevacizumab cetuximab expanded options well. Objective: goals are to review evidence for currently approved with particular attention most recent studies highlighting ideal conditions each. In addition, we discuss current areas investigation – particularly, specific pathway inhibitors that relevant Methods: We used literature well abstracts oral presentations from ASCO AACR meetings. Results/conclusion: report thinking on use present promising novel now being developed