Interpreting the stress response of early mammalian embryos and their stem cells.

摘要: This review analyzes and interprets the normal, pathogenic, pathophysiological roles of stress enzymes in mammalian development. Emerging data suggest that stem cells from early embryos are induced by to perform stress-enzyme-mediated responses use strategies compensatory, prioritized, reversible differentiation. These have been optimized during evolution turn aspects energy conservation optimize maximize efficacy response. It is likely different types varying degrees flexibility mediating compensatory prioritized The significance this analysis interpretation it will serve as a foundation for yielding tools diagnosing, understanding normal mechanisms, providing methods managing improve short- long-term reproductive outcomes.