KIT activation is a ubiquitous feature of gastrointestinal stromal tumors.

作者: David A. Tuveson , George D. Demetri , Anette Duensing , Sheng Xiao , Brian P. Rubin

DOI:

关键词:

摘要:

参考文章(33)
Helen E. Remotti, Frank Aldenborg, Jeanne M. Meis-Kindblom, Lars Gunnar Kindblom, Gastrointestinal pacemaker cell tumor (GIPACT): gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal. American Journal of Pathology. ,vol. 152, pp. 1259- 1269 ,(1998)
Elizabeth S. Russell, Hereditary Anemias of the Mouse: A Review for Geneticists Advances in Genetics. ,vol. 20, pp. 357- 459 ,(1979) , 10.1016/S0065-2660(08)60549-0
T Tsujimura, T Furitsu, M Morimoto, K Isozaki, S Nomura, Y Matsuzawa, Y Kitamura, Y Kanakura, Ligand-independent activation of c-kit receptor tyrosine kinase in a murine mastocytoma cell line P-815 generated by a point mutation Blood. ,vol. 83, pp. 2619- 2626 ,(1994) , 10.1182/BLOOD.V83.9.2619.2619
Y Kitamura, S Go, Decreased production of mast cells in S1/S1d anemic mice Blood. ,vol. 53, pp. 492- 497 ,(1979) , 10.1182/BLOOD.V53.3.492.492
Michael Klüppel, Jan D. Huizinga, John Malysz, Alan Bernstein, Developmental Origin and Kit-Dependent Development of the Interstitial Cells of Cajal in the Mammalian Small Intestine Developmental Dynamics. ,vol. 211, pp. 60- 71 ,(1998) , 10.1002/(SICI)1097-0177(199801)211:1<60::AID-AJA6>3.0.CO;2-5
Jan D. Hulzinga, Lars Thuneberg, Michael Klüppel, John Malysz, Hanne B. Mikkelsen, Alan Bernstein, W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity Nature. ,vol. 373, pp. 347- 349 ,(1995) , 10.1038/373347A0
P. L. Newman, C. Wadden, C. D. M. Fletcher, Gastrointestinal stromal tumours: correlation of immunophenotype with clinicopathological features. The Journal of Pathology. ,vol. 164, pp. 107- 117 ,(1991) , 10.1002/PATH.1711640204
Marcia L. Lux, Brian P. Rubin, Tara L. Biase, Chang-Jie Chen, Timothy Maclure, George Demetri, Sheng Xiao, Samuel Singer, Christopher D.M. Fletcher, Jonathan A. Fletcher, KIT extracellular and kinase domain mutations in gastrointestinal stromal tumors. American Journal of Pathology. ,vol. 156, pp. 791- 795 ,(2000) , 10.1016/S0002-9440(10)64946-2
Yoshio Nakata, Akiro Kimura, Osamd Katoh, Kuniko Kawaishi, Hideo Hyodo, Kazuhiro Abe, Atsushi Kuramoto, Yukio Satow, c-kit point mutation of extracellular domain in patients with myeloproliferative disorders. British Journal of Haematology. ,vol. 91, pp. 661- 663 ,(1995) , 10.1111/J.1365-2141.1995.TB05364.X