Mouse Tumor Model for Neurofibromatosis Type 1 

作者: K. S. Vogel

DOI: 10.1126/SCIENCE.286.5447.2176

关键词: NeurofibromatosisCarcinogenesisMalignant transformationLoss of heterozygosityAlleleGeneticsNeural crestCancer researchSarcomaBiologyTumor suppressor geneMultidisciplinary

摘要: … tumor spectrum in cis-Nf1:p53 mice, we examined the pathological and phenotypic characteristics of the tumors. … Small pieces of tumor tissue were removed for histological processing, …

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