The RB and p53 pathways in cancer

作者: Charles J Sherr , Frank McCormick

DOI: 10.1016/S1535-6108(02)00102-2

关键词: Cell biologyCancer cellSuppressorLife historyTumor cellsCancerSignal transductionTranscription factorRetinoblastoma proteinBiology

摘要: … Most prominent among the regulators disrupted in cancer cells … pathways controlled by RB and p53, attempting to explain their potentially universal involvement in the etiology of cancer. …

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