Effect of the antihistamines, brompheniramine maleate and triprolidine hydrochloride, on performance in man.
作者： AN Nicholson
DOI: 10.1111/J.1365-2125.1979.TB04712.X
关键词:
摘要: 1 Effects of brompheniramine maleate (4 and 12 mg) triprolidine hydrochloride (2.5 10 on visuo-motor coordination, subjective assessments performance, well-being sleep were each studied in six subjects at 0.5, 1.5, 3.0, 5.0 7.0 h after ingestion. The doses refer to immediate sustained release preparations respectively. 2. Triprolidine had an effect performance which persisted 3.0 h, the preparation (10 impaired from 1.5 h. Brompheniramine (12 There no consistent changes or sleep. 3. studies emphasize variable effects antihistamines suggest that may be similar those usual form. Sustained provide advantage clinical practice if antihistaminic activity is prolonged.
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